I’m a postdoctoral researcher in Eric Miska’s group at the Gurdon Institute (University of Cambridge). Before that, I worked with John Marioni at the European Bioinformatics Institute (part of the EMBL). I analyse genomic data to answer biological questions. Here are some of the things I’ve been up to:
My current work is on the regulation of translation in mammals through changes in tRNA abundance and codon usage. I am also looking at the extended polymerase III transcriptome, in particular SINEs. My PhD thesis was titled “Investigating the link between tRNA and mRNA abundance in mammals”.
Before this, I’ve worked in algorithms and software development, in particular implementing high-throughput sequencing read mapping tools, and creating frameworks for the automatic parallelisation of high-performance code on multicore architecture. I have also done work in cell regulatory networks.
I have, at various times, taught on the following subjects:
- High-throughput sequencing with focus on RNA-seq & ChIP-seq (University of Cambridge)
- Computer science 101/102 (Freie Universität Berlin)
- Algorithms in bioinformatics (Freie Universität Berlin)
- Database systems (Freie Universität Berlin)
- C++ (Freie Universität Berlin)
- VB (ActiveVB workshop)
- Unix/Bash (EMBL workshop)
- LaTeX (EMBL workshop)
- R (EMBL workshop)
- Git (EMBL workshop)
Codon-driven translational efficiency is stable across diverse mammalian cell states. PLoS Genet, 12(5): e1006024 (May 2016):
“High-resolution mapping of transcriptional dynamics across tissue development reveals a stable mRNA–tRNA interface”. Genome Res, 24(11):1797–807 (Nov 2014):
* indicates joint first authors
For more, see my Google Scholar profile.
You can follow my activity online: