Hi. My name is Konrad.
I’m a senior research engineer and software developer at PetaGene.
In my previous life I was a postdoctoral researcher in Eric Miska’s group at the University of Cambridge (Gurdon Institute). My PhD was supervised by John Marioni at the European Bioinformatics Institute (EMBL-EBI).
Here are some of the things I do:
I do most of my research on genomics and the regulation of translation in mammals through changes in tRNA abundance and codon usage. The title of my PhD thesis was “Investigating the link between tRNA and mRNA abundance in mammals”.
Before that, I’ve worked in algorithms and software development, in particular implementing high-throughput sequencing read mapping tools, and creating frameworks for the automatic parallelisation of high-performance code on multicore architecture. I have also done work in cell regulatory networks.
Some of my favourite projects are:
A secreted RNA binding protein forms RNA-stabilizing granules in the honeybee royal jelly. Mol Cell, 74, 1–11 (May 2019):
“Codon-driven translational efficiency is stable across diverse mammalian cell states”. PLoS Genet, 12(5): e1006024 (May 2016):
“High-resolution mapping of transcriptional dynamics across tissue development reveals a stable mRNA–tRNA interface”. Genome Res, 24(11):1797–807 (Nov 2014):
For more, see my Google Scholar profile. * indicates joint first authors
I have, at various times, taught on the following subjects:
- High-throughput sequence analysis
- CS 101 & CS 102
- Algorithms in bioinformatics
- Database systems & SQL
- C++ · VB · Unix/Bash · LaTeX · R · Git
I maintain a more or less up-to-date CV as a Developer Story on Stack Overflow.